Sex-linked recessive coagulation disorders primarily affect which gender?

Unlock all questions

This demo includes only 20 questions. Upgrade to access hundreds of questions, flashcards, exam simulations, and disable ads.

Full question bankExam simulationsFlashcards
From $24.99Unlock all

Prepare for the Hemostasis Test with comprehensive quizzes and explanations. Enhance your clinical laboratory science knowledge and ace your exam!

Multiple Choice

Sex-linked recessive coagulation disorders primarily affect which gender?

Explanation:
Sex-linked recessive coagulation disorders are inherited through genes on the X chromosome. In conditions like hemophilia A and B, a mutated gene on the single X chromosome in males leads to deficient clotting factors because there is no second X to compensate. Females have two X chromosomes, so a normal copy on one X usually protects them, making them carriers rather than affected—though rare cases with two mutated Xs or skewed X-inactivation can produce symptoms. This pattern explains why these disorders primarily affect males.

Sex-linked recessive coagulation disorders are inherited through genes on the X chromosome. In conditions like hemophilia A and B, a mutated gene on the single X chromosome in males leads to deficient clotting factors because there is no second X to compensate. Females have two X chromosomes, so a normal copy on one X usually protects them, making them carriers rather than affected—though rare cases with two mutated Xs or skewed X-inactivation can produce symptoms. This pattern explains why these disorders primarily affect males.

More Multiple Choice Questions
Subscribe

Get the latest from Examzify

You can unsubscribe at any time. Read our privacy policy