Which of the following enzymatically de-grades the stabilized fibrin clot?

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Multiple Choice

Which of the following enzymatically de-grades the stabilized fibrin clot?

Explanation:
Fibrinolysis—the enzymatic breakdown of a formed fibrin clot. After a clot is created and stabilized by cross-linking from factor XIII, the body uses plasmin to dissolve the clot. Plasmin is formed from its inactive precursor plasminogen by activators such as tissue plasminogen activator (tPA) or urokinase. Once active, plasmin cleaves the fibrin mesh into soluble fragments, leading to clot dissolution. Prothrombin and thrombin are involved in forming clots, not breaking them down, and plasminogen must be activated to become plasmin. So the enzyme that degrades the stabilized fibrin clot is plasmin.

Fibrinolysis—the enzymatic breakdown of a formed fibrin clot. After a clot is created and stabilized by cross-linking from factor XIII, the body uses plasmin to dissolve the clot. Plasmin is formed from its inactive precursor plasminogen by activators such as tissue plasminogen activator (tPA) or urokinase. Once active, plasmin cleaves the fibrin mesh into soluble fragments, leading to clot dissolution. Prothrombin and thrombin are involved in forming clots, not breaking them down, and plasminogen must be activated to become plasmin. So the enzyme that degrades the stabilized fibrin clot is plasmin.

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