Which statement best describes protein C?

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Multiple Choice

Which statement best describes protein C?

Explanation:
Protein C is a vitamin K–dependent anticoagulant protein produced by the liver. On the endothelial surface, thrombin bound to thrombomodulin activates protein C, and the activated form (with protein S as a cofactor) inactivates factors Va and VIIIa, reducing thrombin generation and curbing clot formation. That makes it an inhibitor of clotting. It does not activate Va or VIII:C; it does not primarily inhibit fibrinolysis; and it is produced by the liver, not the endothelium. Therefore, the best description is that protein C is a vitamin K–dependent inhibitor to clotting.

Protein C is a vitamin K–dependent anticoagulant protein produced by the liver. On the endothelial surface, thrombin bound to thrombomodulin activates protein C, and the activated form (with protein S as a cofactor) inactivates factors Va and VIIIa, reducing thrombin generation and curbing clot formation. That makes it an inhibitor of clotting. It does not activate Va or VIII:C; it does not primarily inhibit fibrinolysis; and it is produced by the liver, not the endothelium. Therefore, the best description is that protein C is a vitamin K–dependent inhibitor to clotting.

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